Urea Amidolyase (DUR1,2) Contributes to Virulence and Kidney Pathogenesis of Candida albicans

The intracellular enzyme urea amidolyase (Dur1,2p) enables C. albicans to utilize urea as a sole nitrogen source. Because deletion of the DUR1,2 gene reduces survival of C. albicans co-cultured with a murine macrophage cell line, we investigated the role of Dur1,2p in pathogenesis using a mouse mode...

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Detalles Bibliográficos
Autores principales: Navarathna, Dhammika H. M. L. P., Lionakis, Michail S., Lizak, Martin J., Munasinghe, Jeeva, Nickerson, Kenneth W., Roberts, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483220/
https://www.ncbi.nlm.nih.gov/pubmed/23144764
http://dx.doi.org/10.1371/journal.pone.0048475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483220/
https://www.ncbi.nlm.nih.gov/pubmed/23144764
http://dx.doi.org/10.1371/journal.pone.0048475

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