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Genome-Wide Association Study Heterogeneous Cohort Homogenization via Subject Weight Knock-Down
Population structure can be a source of both false-positive and false-negative findings in a genome-wide association study. This article proposes an approach that helps to reduce the false-positives. It consists of homogenizing the diseased/healthy phenotype ratio across the cohort, by decreasing th...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483272/ https://www.ncbi.nlm.nih.gov/pubmed/23144770 http://dx.doi.org/10.1371/journal.pone.0048653 |