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In Vitro Immunomodulation of a Whole Blood IFN-γ Release Assay Enhances T Cell Responses in Subjects with Latent Tuberculosis Infection

BACKGROUND: Activation of innate immunity via pathogen recognition receptors (PRR) modulates adaptive immune responses. PRR ligands are being exploited as vaccine adjuvants and as therapeutics, but their utility in diagnostics has not been explored. Interferon-gamma (IFN-γ) release assays (IGRAs) ar...

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Detalles Bibliográficos
Autores principales:	Gaur, Rajiv L., Suhosk, Megan M., Banaei, Niaz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483295/ https://www.ncbi.nlm.nih.gov/pubmed/23144722 http://dx.doi.org/10.1371/journal.pone.0048027

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