Development of a Quantitative Methylation-Specific Polymerase Chain Reaction Method for Monitoring Beta Cell Death in Type 1 Diabetes

DNA methylation is a mechanism by which cells control gene expression, and cell-specific genes often exhibit unique patterns of DNA methylation. We previously reported that the mouse insulin-2 gene (Ins2) promoter has three potential methylation (CpG) sites, all of which are unmethylated in insulin-...

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Detalles Bibliográficos
Autores principales: Husseiny, Mohamed I., Kuroda, Akio, Kaye, Alexander N., Nair, Indu, Kandeel, Fouad, Ferreri, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483298/
https://www.ncbi.nlm.nih.gov/pubmed/23144715
http://dx.doi.org/10.1371/journal.pone.0047942

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