Cargando…

A functional methylome map of ulcerative colitis

The etiology of inflammatory bowel diseases is only partially explained by the current genetic risk map. It is hypothesized that environmental factors modulate the epigenetic landscape and thus contribute to disease susceptibility, manifestation, and progression. To test this, we analyzed DNA methyl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Häsler, Robert, Feng, Zhe, Bäckdahl, Liselotte, Spehlmann, Martina E., Franke, Andre, Teschendorff, Andrew, Rakyan, Vardhman K., Down, Thomas A., Wilson, Gareth A., Feber, Andrew, Beck, Stephan, Schreiber, Stefan, Rosenstiel, Philip
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483542/ https://www.ncbi.nlm.nih.gov/pubmed/22826509 http://dx.doi.org/10.1101/gr.138347.112

Ejemplares similares

The human blood DNA methylome displays a highly distinctive profile compared with other somatic tissues
por: Lowe, Robert, et al.
Publicado: (2015)

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus
por: Bell, Christopher G, et al.
Publicado: (2010)

Genome Wide Analysis of Acute Myeloid Leukemia Reveal Leukemia Specific Methylome and Subtype Specific Hypomethylation of Repeats
por: Saied, Marwa H., et al.
Publicado: (2012)

Resources for methylome analysis suitable for gene knockout studies of potential epigenome modifiers
por: Wilson, Gareth A, et al.
Publicado: (2012)

Guthrie card methylomics identifies temporally stable epialleles that are present at birth in humans
por: Beyan, Huriya, et al.
Publicado: (2012)

Correlation of an epigenetic mitotic clock with cancer risk
por: Yang, Zhen, et al.
Publicado: (2016)

Integrated virus-host methylome analysis in head and neck squamous cell carcinoma
por: Wilson, Gareth A, et al.
Publicado: (2013)

EPISCORE: cell type deconvolution of bulk tissue DNA methylomes from single-cell RNA-Seq data
por: Teschendorff, Andrew E., et al.
Publicado: (2020)

Genome-wide rare copy number variation screening in ulcerative colitis identifies potential susceptibility loci
por: Saadati, Hamid Reza, et al.
Publicado: (2016)

Comments on: Interpretation of genome-wide infinium methylation data from ligated DNA in formalin-fixed paraffin-embedded paired tumor and normal tissue
por: Thirlwell, Christina, et al.
Publicado: (2012)

The hunt for mammalian epialleles
por: Rakyan, Vardhman
Publicado: (2012)

The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans
por: Lowe, Robert, et al.
Publicado: (2015)

Generation of a genomic tiling array of the human Major Histocompatibility Complex (MHC) and its application for DNA methylation analysis
por: Tomazou, Eleni M, et al.
Publicado: (2008)

Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus
por: Bell, Christopher G., et al.
Publicado: (2010)

The DNA methylome of human sperm is distinct from blood with little evidence for tissue-consistent obesity associations
por: Åsenius, Fredrika, et al.
Publicado: (2020)

Whole genome and exome sequencing of monozygotic twins discordant for Crohn’s disease
por: Petersen, Britt-Sabina, et al.
Publicado: (2014)

Correcting for cell-type composition bias in epigenome-wide association studies
por: Lowe, Robert, et al.
Publicado: (2014)

Marmal-aid – a database for Infinium HumanMethylation450
por: Lowe, Robert, et al.
Publicado: (2013)

The multi-omic landscape of transcription factor inactivation in cancer
por: Teschendorff, Andrew E., et al.
Publicado: (2016)

A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolution
por: Zhu, Tianyu, et al.
Publicado: (2022)

ChAMP: updated methylation analysis pipeline for Illumina BeadChips
por: Tian, Yuan, et al.
Publicado: (2017)

Placenta-specific Methylation of the Vitamin D 24-Hydroxylase Gene: IMPLICATIONS FOR FEEDBACK AUTOREGULATION OF ACTIVE VITAMIN D LEVELS AT THE FETOMATERNAL INTERFACE
por: Novakovic, Boris, et al.
Publicado: (2009)

DNA Methylation-mediated Down-regulation of DNA Methyltransferase-1 (DNMT1) Is Coincident with, but Not Essential for, Global Hypomethylation in Human Placenta
por: Novakovic, Boris, et al.
Publicado: (2010)

BulkVis: a graphical viewer for Oxford nanopore bulk FAST5 files
por: Payne, Alexander, et al.
Publicado: (2019)

Ulcerative Colitis: Shifting Sands
por: D’Haens, Geert R. A. M., et al.
Publicado: (2019)

Using high-density DNA methylation arrays to profile copy number alterations
por: Feber, Andrew, et al.
Publicado: (2014)

Glioblastoma Stem Cells Respond to Differentiation Cues but Fail to Undergo Commitment and Terminal Cell-Cycle Arrest
por: Carén, Helena, et al.
Publicado: (2015)

Genome-Wide Screen for Differential DNA Methylation Associated with Neural Cell Differentiation in Mouse
por: Cortese, Rene, et al.
Publicado: (2011)

Sexually dimorphic gene expression emerges with embryonic genome activation and is dynamic throughout development
por: Lowe, Robert, et al.
Publicado: (2015)

Base-pair resolution DNA methylome of the EBV-positive Endemic Burkitt lymphoma cell line DAUDI determined by SOLiD bisulfite-sequencing
por: Kreck, B, et al.
Publicado: (2013)

Golimumab in unresponsive ulcerative colitis
por: Lippert, Elisabeth, et al.
Publicado: (2014)

A donor-specific epigenetic classifier for acute graft-versus-host disease severity in hematopoietic stem cell transplantation
por: Paul, Dirk S., et al.
Publicado: (2015)

Age-associated epigenetic drift: implications, and a case of epigenetic thrift?
por: Teschendorff, Andrew E., et al.
Publicado: (2013)

ULCERATIVE COLITIS
Publicado: (1969)

Tofacitinib for the Treatment of Ulcerative Colitis: Analysis of Infection Rates from the Ulcerative Colitis Clinical Programme
por: Winthrop, Kevin L, et al.
Publicado: (2020)

Mapping the minutiae of the human methylome
por: Minton, Kirsty
Publicado: (2023)

Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development
por: Pan, Wei-Hung, et al.
Publicado: (2018)

Meta-analysis of IDH-mutant cancers identifies EBF1 as an interaction partner for TET2
por: Guilhamon, Paul, et al.
Publicado: (2013)

Identification of Type 1 Diabetes–Associated DNA Methylation Variable Positions That Precede Disease Diagnosis
por: Rakyan, Vardhman K., et al.
Publicado: (2011)

Early life diet conditions the molecular response to post-weaning protein restriction in the mouse
por: Danson, Amy F., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_tsqjuo0luhb2vccpqqkchokgag