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Guthrie card methylomics identifies temporally stable epialleles that are present at birth in humans
A major concern in common disease epigenomics is distinguishing causal from consequential epigenetic variation. One means of addressing this issue is to identify the temporal origins of epigenetic variants via longitudinal analyses. However, prospective birth-cohort studies are expensive and time co...
Autores principales: | Beyan, Huriya, Down, Thomas A., Ramagopalan, Sreeram V., Uvebrant, Kristina, Nilsson, Anita, Holland, Michelle L., Gemma, Carolina, Giovannoni, Gavin, Boehm, Bernhard O., Ebers, George C., Lernmark, Åke, Cilio, Corrado M., Leslie, R. David, Rakyan, Vardhman K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483543/ https://www.ncbi.nlm.nih.gov/pubmed/22919074 http://dx.doi.org/10.1101/gr.134304.111 |
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