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Guthrie card methylomics identifies temporally stable epialleles that are present at birth in humans

A major concern in common disease epigenomics is distinguishing causal from consequential epigenetic variation. One means of addressing this issue is to identify the temporal origins of epigenetic variants via longitudinal analyses. However, prospective birth-cohort studies are expensive and time co...

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Detalles Bibliográficos
Autores principales: Beyan, Huriya, Down, Thomas A., Ramagopalan, Sreeram V., Uvebrant, Kristina, Nilsson, Anita, Holland, Michelle L., Gemma, Carolina, Giovannoni, Gavin, Boehm, Bernhard O., Ebers, George C., Lernmark, Åke, Cilio, Corrado M., Leslie, R. David, Rakyan, Vardhman K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483543/
https://www.ncbi.nlm.nih.gov/pubmed/22919074
http://dx.doi.org/10.1101/gr.134304.111

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