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Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules
The cohesin protein complex contributes to transcriptional regulation in a CTCF-independent manner by colocalizing with master regulators at tissue-specific loci. The regulation of transcription involves the concerted action of multiple transcription factors (TFs) and cohesin's role in this con...
Autores principales: | Faure, Andre J., Schmidt, Dominic, Watt, Stephen, Schwalie, Petra C., Wilson, Michael D., Xu, Huiling, Ramsay, Robert G., Odom, Duncan T., Flicek, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483546/ https://www.ncbi.nlm.nih.gov/pubmed/22780989 http://dx.doi.org/10.1101/gr.136507.111 |
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