Genome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting

So far, the annotation of translation initiation sites (TISs) has been based mostly upon bioinformatics rather than experimental evidence. We adapted ribosomal footprinting to puromycin-treated cells to generate a transcriptome-wide map of TISs in a human monocytic cell line. A neural network was tr...

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Detalles Bibliográficos
Autores principales: Fritsch, Claudia, Herrmann, Alexander, Nothnagel, Michael, Szafranski, Karol, Huse, Klaus, Schumann, Frank, Schreiber, Stefan, Platzer, Matthias, Krawczak, Michael, Hampe, Jochen, Brosch, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483550/
https://www.ncbi.nlm.nih.gov/pubmed/22879431
http://dx.doi.org/10.1101/gr.139568.112

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