Cargando…

Two Cases of Diffuse Duodenitis Associated with Ulcerative Colitis

The upper gastrointestinal tract is not generally considered a target organ in ulcerative colitis (UC). However, several cases showing upper gastrointestinal involvement in UC have been reported. In this report, we present 2 rare cases of diffuse duodenitis accompanying pancolonic UC. Case patient 1...

Descripción completa

Detalles Bibliográficos
Autores principales: Endo, Katsuya, Kuroha, Masatake, Shiga, Hisashi, Kakuta, Yoichi, Takahashi, Seiichi, Kinouchi, Yoshitaka, Shimosegawa, Tooru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483663/
https://www.ncbi.nlm.nih.gov/pubmed/23119193
http://dx.doi.org/10.1155/2012/396521
_version_ 1782248036931469312
author Endo, Katsuya
Kuroha, Masatake
Shiga, Hisashi
Kakuta, Yoichi
Takahashi, Seiichi
Kinouchi, Yoshitaka
Shimosegawa, Tooru
author_facet Endo, Katsuya
Kuroha, Masatake
Shiga, Hisashi
Kakuta, Yoichi
Takahashi, Seiichi
Kinouchi, Yoshitaka
Shimosegawa, Tooru
author_sort Endo, Katsuya
collection PubMed
description The upper gastrointestinal tract is not generally considered a target organ in ulcerative colitis (UC). However, several cases showing upper gastrointestinal involvement in UC have been reported. In this report, we present 2 rare cases of diffuse duodenitis accompanying pancolonic UC. Case patient 1 was a 44-year-old man who developed diffuse duodenitis shortly after colectomy and was successfully treated with mesalazine. Case patient 2 was a 25-year-old woman who developed diffuse duodenitis under a steroid-free condition and was successfully treated with prednisolone. The 2 patients had Helicobacter pylori-negative duodenitis that resembled colonic lesions of UC in both the endoscopic and histological findings. No evidence of Crohn's disease was found in these cases. We diagnosed both cases as typical UC-associated diffuse duodenitis. The occurrence of gastrointestinal involvement in UC has been attracting attention because such lesions could potentially open a new window for studying the etiology and pathogenesis of UC. Further studies involving a large number of patients are needed to clarify whether the upper gastrointestinal tract is a target organ in UC.
format Online
Article
Text
id pubmed-3483663
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-34836632012-11-01 Two Cases of Diffuse Duodenitis Associated with Ulcerative Colitis Endo, Katsuya Kuroha, Masatake Shiga, Hisashi Kakuta, Yoichi Takahashi, Seiichi Kinouchi, Yoshitaka Shimosegawa, Tooru Case Rep Gastrointest Med Case Report The upper gastrointestinal tract is not generally considered a target organ in ulcerative colitis (UC). However, several cases showing upper gastrointestinal involvement in UC have been reported. In this report, we present 2 rare cases of diffuse duodenitis accompanying pancolonic UC. Case patient 1 was a 44-year-old man who developed diffuse duodenitis shortly after colectomy and was successfully treated with mesalazine. Case patient 2 was a 25-year-old woman who developed diffuse duodenitis under a steroid-free condition and was successfully treated with prednisolone. The 2 patients had Helicobacter pylori-negative duodenitis that resembled colonic lesions of UC in both the endoscopic and histological findings. No evidence of Crohn's disease was found in these cases. We diagnosed both cases as typical UC-associated diffuse duodenitis. The occurrence of gastrointestinal involvement in UC has been attracting attention because such lesions could potentially open a new window for studying the etiology and pathogenesis of UC. Further studies involving a large number of patients are needed to clarify whether the upper gastrointestinal tract is a target organ in UC. Hindawi Publishing Corporation 2012 2012-10-17 /pmc/articles/PMC3483663/ /pubmed/23119193 http://dx.doi.org/10.1155/2012/396521 Text en Copyright © 2012 Katsuya Endo et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Endo, Katsuya
Kuroha, Masatake
Shiga, Hisashi
Kakuta, Yoichi
Takahashi, Seiichi
Kinouchi, Yoshitaka
Shimosegawa, Tooru
Two Cases of Diffuse Duodenitis Associated with Ulcerative Colitis
title Two Cases of Diffuse Duodenitis Associated with Ulcerative Colitis
title_full Two Cases of Diffuse Duodenitis Associated with Ulcerative Colitis
title_fullStr Two Cases of Diffuse Duodenitis Associated with Ulcerative Colitis
title_full_unstemmed Two Cases of Diffuse Duodenitis Associated with Ulcerative Colitis
title_short Two Cases of Diffuse Duodenitis Associated with Ulcerative Colitis
title_sort two cases of diffuse duodenitis associated with ulcerative colitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483663/
https://www.ncbi.nlm.nih.gov/pubmed/23119193
http://dx.doi.org/10.1155/2012/396521
work_keys_str_mv AT endokatsuya twocasesofdiffuseduodenitisassociatedwithulcerativecolitis
AT kurohamasatake twocasesofdiffuseduodenitisassociatedwithulcerativecolitis
AT shigahisashi twocasesofdiffuseduodenitisassociatedwithulcerativecolitis
AT kakutayoichi twocasesofdiffuseduodenitisassociatedwithulcerativecolitis
AT takahashiseiichi twocasesofdiffuseduodenitisassociatedwithulcerativecolitis
AT kinouchiyoshitaka twocasesofdiffuseduodenitisassociatedwithulcerativecolitis
AT shimosegawatooru twocasesofdiffuseduodenitisassociatedwithulcerativecolitis