Ileal Inflammation May Trigger the Development of GP2-Specific Pancreatic Autoantibodies in Patients with Crohn's Disease

Why zymogen glycoprotein 2 (GP2), the Crohn's disease (CD)-specific pancreatic autoantigen, is the major target of humoral autoimmunity in inflammatory bowel diseases (IBD) is uknown. Recent evidence demonstrates that GP2 is also present on the apical surface of microfold (M) intestinal cells....

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Detalles Bibliográficos
Autores principales: Pavlidis, Polychronis, Romanidou, Ourania, Roggenbuck, Dirk, Mytilinaiou, Maria G., Al-Sulttan, Faris, Liaskos, Christos, Smyk, Daniel S., Koutsoumpas, Andreas L., Rigopoulou, Eirini I., Conrad, Karsten, Forbes, Alastair, Bogdanos, Dimitrios P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483735/
https://www.ncbi.nlm.nih.gov/pubmed/23118780
http://dx.doi.org/10.1155/2012/640835

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