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Systems Biology of Meridians, Acupoints, and Chinese Herbs in Disease

Meridians, acupoints, and Chinese herbs are important components of traditional Chinese medicine (TCM). They have been used for disease treatment and prevention and as alternative and complementary therapies. Systems biology integrates omics data, such as transcriptional, proteomic, and metabolomics...

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Autores principales: Lin, Li-Ling, Wang, Ya-Hui, Lai, Chi-Yu, Chau, Chan-Lao, Su, Guan-Chin, Yang, Chun-Yi, Lou, Shu-Ying, Chen, Szu-Kai, Hsu, Kuan-Hao, Lai, Yen-Ling, Wu, Wei-Ming, Huang, Jian-Long, Liao, Chih-Hsin, Juan, Hsueh-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483864/
https://www.ncbi.nlm.nih.gov/pubmed/23118787
http://dx.doi.org/10.1155/2012/372670
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author Lin, Li-Ling
Wang, Ya-Hui
Lai, Chi-Yu
Chau, Chan-Lao
Su, Guan-Chin
Yang, Chun-Yi
Lou, Shu-Ying
Chen, Szu-Kai
Hsu, Kuan-Hao
Lai, Yen-Ling
Wu, Wei-Ming
Huang, Jian-Long
Liao, Chih-Hsin
Juan, Hsueh-Fen
author_facet Lin, Li-Ling
Wang, Ya-Hui
Lai, Chi-Yu
Chau, Chan-Lao
Su, Guan-Chin
Yang, Chun-Yi
Lou, Shu-Ying
Chen, Szu-Kai
Hsu, Kuan-Hao
Lai, Yen-Ling
Wu, Wei-Ming
Huang, Jian-Long
Liao, Chih-Hsin
Juan, Hsueh-Fen
author_sort Lin, Li-Ling
collection PubMed
description Meridians, acupoints, and Chinese herbs are important components of traditional Chinese medicine (TCM). They have been used for disease treatment and prevention and as alternative and complementary therapies. Systems biology integrates omics data, such as transcriptional, proteomic, and metabolomics data, in order to obtain a more global and complete picture of biological activity. To further understand the existence and functions of the three components above, we reviewed relevant research in the systems biology literature and found many recent studies that indicate the value of acupuncture and Chinese herbs. Acupuncture is useful in pain moderation and relieves various symptoms arising from acute spinal cord injury and acute ischemic stroke. Moreover, Chinese herbal extracts have been linked to wound repair, the alleviation of postmenopausal osteoporosis severity, and anti-tumor effects, among others. Different acupoints, variations in treatment duration, and herbal extracts can be used to alleviate various symptoms and conditions and to regulate biological pathways by altering gene and protein expression. Our paper demonstrates how systems biology has helped to establish a platform for investigating the efficacy of TCM in treating different diseases and improving treatment strategies.
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spelling pubmed-34838642012-11-01 Systems Biology of Meridians, Acupoints, and Chinese Herbs in Disease Lin, Li-Ling Wang, Ya-Hui Lai, Chi-Yu Chau, Chan-Lao Su, Guan-Chin Yang, Chun-Yi Lou, Shu-Ying Chen, Szu-Kai Hsu, Kuan-Hao Lai, Yen-Ling Wu, Wei-Ming Huang, Jian-Long Liao, Chih-Hsin Juan, Hsueh-Fen Evid Based Complement Alternat Med Review Article Meridians, acupoints, and Chinese herbs are important components of traditional Chinese medicine (TCM). They have been used for disease treatment and prevention and as alternative and complementary therapies. Systems biology integrates omics data, such as transcriptional, proteomic, and metabolomics data, in order to obtain a more global and complete picture of biological activity. To further understand the existence and functions of the three components above, we reviewed relevant research in the systems biology literature and found many recent studies that indicate the value of acupuncture and Chinese herbs. Acupuncture is useful in pain moderation and relieves various symptoms arising from acute spinal cord injury and acute ischemic stroke. Moreover, Chinese herbal extracts have been linked to wound repair, the alleviation of postmenopausal osteoporosis severity, and anti-tumor effects, among others. Different acupoints, variations in treatment duration, and herbal extracts can be used to alleviate various symptoms and conditions and to regulate biological pathways by altering gene and protein expression. Our paper demonstrates how systems biology has helped to establish a platform for investigating the efficacy of TCM in treating different diseases and improving treatment strategies. Hindawi Publishing Corporation 2012 2012-10-18 /pmc/articles/PMC3483864/ /pubmed/23118787 http://dx.doi.org/10.1155/2012/372670 Text en Copyright © 2012 Li-Ling Lin et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Lin, Li-Ling
Wang, Ya-Hui
Lai, Chi-Yu
Chau, Chan-Lao
Su, Guan-Chin
Yang, Chun-Yi
Lou, Shu-Ying
Chen, Szu-Kai
Hsu, Kuan-Hao
Lai, Yen-Ling
Wu, Wei-Ming
Huang, Jian-Long
Liao, Chih-Hsin
Juan, Hsueh-Fen
Systems Biology of Meridians, Acupoints, and Chinese Herbs in Disease
title Systems Biology of Meridians, Acupoints, and Chinese Herbs in Disease
title_full Systems Biology of Meridians, Acupoints, and Chinese Herbs in Disease
title_fullStr Systems Biology of Meridians, Acupoints, and Chinese Herbs in Disease
title_full_unstemmed Systems Biology of Meridians, Acupoints, and Chinese Herbs in Disease
title_short Systems Biology of Meridians, Acupoints, and Chinese Herbs in Disease
title_sort systems biology of meridians, acupoints, and chinese herbs in disease
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483864/
https://www.ncbi.nlm.nih.gov/pubmed/23118787
http://dx.doi.org/10.1155/2012/372670
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