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An expanding role for cell biologists in drug discovery and pharmacology

The profound challenges facing clinicians, who must prescribe drugs in the face of dramatic variability in response, and the pharmaceutical industry, which must develop new drugs despite ever-rising costs, represent opportunities for cell biologists interested in rethinking the conceptual basis of p...

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Detalles Bibliográficos
Autores principales: Sorger, Peter K., Schoeberl, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484093/
https://www.ncbi.nlm.nih.gov/pubmed/23112228
http://dx.doi.org/10.1091/mbc.E12-05-0394
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author Sorger, Peter K.
Schoeberl, Birgit
author_facet Sorger, Peter K.
Schoeberl, Birgit
author_sort Sorger, Peter K.
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description The profound challenges facing clinicians, who must prescribe drugs in the face of dramatic variability in response, and the pharmaceutical industry, which must develop new drugs despite ever-rising costs, represent opportunities for cell biologists interested in rethinking the conceptual basis of pharmacology and drug discovery. Much better understanding is required of the quantitative behaviors of networks targeted by drugs in cells, tissues, and organisms. Cell biologists interested in these topics should learn more about the basic structure of drug development campaigns and hone their quantitative and programming skills. A world of conceptual challenges and engaging industry–academic collaborations awaits, all with the promise of delivering real benefit to patients and strained healthcare systems.
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spelling pubmed-34840932013-01-16 An expanding role for cell biologists in drug discovery and pharmacology Sorger, Peter K. Schoeberl, Birgit Mol Biol Cell Perspectives The profound challenges facing clinicians, who must prescribe drugs in the face of dramatic variability in response, and the pharmaceutical industry, which must develop new drugs despite ever-rising costs, represent opportunities for cell biologists interested in rethinking the conceptual basis of pharmacology and drug discovery. Much better understanding is required of the quantitative behaviors of networks targeted by drugs in cells, tissues, and organisms. Cell biologists interested in these topics should learn more about the basic structure of drug development campaigns and hone their quantitative and programming skills. A world of conceptual challenges and engaging industry–academic collaborations awaits, all with the promise of delivering real benefit to patients and strained healthcare systems. The American Society for Cell Biology 2012-11-01 /pmc/articles/PMC3484093/ /pubmed/23112228 http://dx.doi.org/10.1091/mbc.E12-05-0394 Text en © 2012 Sorger and Schoeberl. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0). “ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society of Cell BD; are registered trademarks of The American Society of Cell Biology.
spellingShingle Perspectives
Sorger, Peter K.
Schoeberl, Birgit
An expanding role for cell biologists in drug discovery and pharmacology
title An expanding role for cell biologists in drug discovery and pharmacology
title_full An expanding role for cell biologists in drug discovery and pharmacology
title_fullStr An expanding role for cell biologists in drug discovery and pharmacology
title_full_unstemmed An expanding role for cell biologists in drug discovery and pharmacology
title_short An expanding role for cell biologists in drug discovery and pharmacology
title_sort expanding role for cell biologists in drug discovery and pharmacology
topic Perspectives
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484093/
https://www.ncbi.nlm.nih.gov/pubmed/23112228
http://dx.doi.org/10.1091/mbc.E12-05-0394
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