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SLAC, a complex between Sla1 and Las17, regulates actin polymerization during clathrin-mediated endocytosis

During clathrin-mediated endocytosis, branched actin polymerization nucleated by the Arp2/3 complex provides force needed to drive vesicle internalization. Las17 (yeast WASp) is the strongest activator of the Arp2/3 complex in yeast cells; it is not autoinhibited and arrives to endocytic sites 20 s...

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Detalles Bibliográficos
Autores principales: Feliciano, Daniel, Di Pietro, Santiago M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484103/
https://www.ncbi.nlm.nih.gov/pubmed/22973053
http://dx.doi.org/10.1091/mbc.E11-12-1022

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