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Human RECQL5 participates in the removal of endogenous DNA damage

Human RECQL5 is a member of the RecQ helicase family, which maintains genome stability via participation in many DNA metabolic processes, including DNA repair. Human cells lacking RECQL5 display chromosomal instability. We find that cells depleted of RECQL5 are sensitive to oxidative stress, accumul...

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Detalles Bibliográficos
Autores principales:	Tadokoro, Takashi, Ramamoorthy, Mahesh, Popuri, Venkateswarlu, May, Alfred, Tian, Jingyan, Sykora, Peter, Rybanska, Ivana, Wilson, David M., Croteau, Deborah L., Bohr, Vilhelm A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484104/ https://www.ncbi.nlm.nih.gov/pubmed/22973052 http://dx.doi.org/10.1091/mbc.E12-02-0110

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