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Nucleolar AATF regulates c-Jun–mediated apoptosis

The AP-1 transcription factor c-Jun has been shown to be essential for stress-induced apoptosis in several models. However, the molecular mechanisms underlying the proapoptotic activity of c-Jun are poorly understood. We identify the apoptosis-antagonizing transcription factor (AATF) as a novel nucl...

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Detalles Bibliográficos
Autores principales: Ferraris, Saima E., Isoniemi, Kimmo, Torvaldson, Elin, Anckar, Julius, Westermarck, Jukka, Eriksson, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484108/
https://www.ncbi.nlm.nih.gov/pubmed/22933572
http://dx.doi.org/10.1091/mbc.E12-05-0419