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Docosahexaenoic Acid Signaling Modulates Cell Survival in Experimental Ischemic Stroke Penumbra and Initiates Long-Term Repair in Young and Aged Rats
BACKGROUND: Docosahexaenoic acid, a major omega-3 essential fatty acid family member, improves behavioral deficit and reduces infarct volume and edema after experimental focal cerebral ischemia. We hypothesize that DHA elicits neuroprotection by inducing AKT/p70S6K phosphorylation, which in turn lea...
Autores principales: | Eady, Tiffany N., Belayev, Ludmila, Khoutorova, Larissa, Atkins, Kristal D., Zhang, Changde, Bazan, Nicolas G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484151/ https://www.ncbi.nlm.nih.gov/pubmed/23118851 http://dx.doi.org/10.1371/journal.pone.0046151 |
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