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HOTAIR IS A NEGATIVE PROGNOSTIC FACTOR AND EXHIBITS PRO-ONCOGENIC ACTIVITY IN PANCREATIC CANCER
HOTAIR is a long intervening non-coding RNA (lincRNA) that associates with the Polycomb Repressive Complex 2 (PRC2) and overexpression is correlated with poor survival for breast, colon and liver cancer patients. In this study, we show that HOTAIR expression is increased in pancreatic tumors compare...
Autores principales: | Kim, Kyounghyun, Jutooru, Indira, Chadalapaka, Gayathri, Johnson, Greg, Frank, James, Burghardt, Robert, Kim, Sangbae, Safe, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484248/ https://www.ncbi.nlm.nih.gov/pubmed/22614017 http://dx.doi.org/10.1038/onc.2012.193 |
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