High-sensitivity C-reactive protein (hs-CRP) and tumor necrotizing factor-alpha (TNF-alpha) after on- and off- pump coronary artery bypass grafting

INTRODUCTION: Coronary artery bypass grafting (CABG) is one of the most frequently performed operations around the world. The aim of this study is to evaluate high-sensitivity C-reactive protein (hs-CRP) and tumor necrosis factor-alpha (TNF-alpha) differences between on-pump and off-pump coronary su...

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Autores principales: Javadzadegan, H, Nezami, N, Ghobadi, K, Sadighi, A, Abolfathi, A A, Nader, N D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDIMES Edizioni Internazionali Srl 2010
Materias:
Research-Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484567/
https://www.ncbi.nlm.nih.gov/pubmed/23439767
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author Javadzadegan, H
Nezami, N
Ghobadi, K
Sadighi, A
Abolfathi, A A
Nader, N D
author_facet Javadzadegan, H
Nezami, N
Ghobadi, K
Sadighi, A
Abolfathi, A A
Nader, N D
author_sort Javadzadegan, H
collection PubMed
description INTRODUCTION: Coronary artery bypass grafting (CABG) is one of the most frequently performed operations around the world. The aim of this study is to evaluate high-sensitivity C-reactive protein (hs-CRP) and tumor necrosis factor-alpha (TNF-alpha) differences between on-pump and off-pump coronary surgery. METHODS: In this prospective study, 90 patients with coronary artery disease referred for CABG were enrolled from July 2006-November 2007. Levels of hs-CRP and TNF-alpha were measured by ELISA using commercial kits RESULTS: hs-CRP levels significantly (p<0.001) increase after CABG. But no difference between off-pump and on-pump groups was noted for hs-CRP and TNF-alpha levels (p=0.4, p=0.8). CONCLUSIONS: There was no difference in high-sensitivity C-reactive protein (hs-CRP) and TNF-alpha between on-pump and off-pump CABG surgery.
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spelling pubmed-34845672013-02-25 High-sensitivity C-reactive protein (hs-CRP) and tumor necrotizing factor-alpha (TNF-alpha) after on- and off- pump coronary artery bypass grafting Javadzadegan, H Nezami, N Ghobadi, K Sadighi, A Abolfathi, A A Nader, N D HSR Proc Intensive Care Cardiovasc Anesth Research-Article INTRODUCTION: Coronary artery bypass grafting (CABG) is one of the most frequently performed operations around the world. The aim of this study is to evaluate high-sensitivity C-reactive protein (hs-CRP) and tumor necrosis factor-alpha (TNF-alpha) differences between on-pump and off-pump coronary surgery. METHODS: In this prospective study, 90 patients with coronary artery disease referred for CABG were enrolled from July 2006-November 2007. Levels of hs-CRP and TNF-alpha were measured by ELISA using commercial kits RESULTS: hs-CRP levels significantly (p<0.001) increase after CABG. But no difference between off-pump and on-pump groups was noted for hs-CRP and TNF-alpha levels (p=0.4, p=0.8). CONCLUSIONS: There was no difference in high-sensitivity C-reactive protein (hs-CRP) and TNF-alpha between on-pump and off-pump CABG surgery. EDIMES Edizioni Internazionali Srl 2010 /pmc/articles/PMC3484567/ /pubmed/23439767 Text en Copyright © 2010, HSR Proceedings in Intensive Care and Cardiovascular Anesthesia http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License 3.0, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. See: http://creativecommons.org/licenses/by-nc/3.0/ and http://creativecommons.org/licenses/by-nc/3.0/legalcode.
spellingShingle Research-Article
Javadzadegan, H
Nezami, N
Ghobadi, K
Sadighi, A
Abolfathi, A A
Nader, N D
High-sensitivity C-reactive protein (hs-CRP) and tumor necrotizing factor-alpha (TNF-alpha) after on- and off- pump coronary artery bypass grafting
title High-sensitivity C-reactive protein (hs-CRP) and tumor necrotizing factor-alpha (TNF-alpha) after on- and off- pump coronary artery bypass grafting
title_full High-sensitivity C-reactive protein (hs-CRP) and tumor necrotizing factor-alpha (TNF-alpha) after on- and off- pump coronary artery bypass grafting
title_fullStr High-sensitivity C-reactive protein (hs-CRP) and tumor necrotizing factor-alpha (TNF-alpha) after on- and off- pump coronary artery bypass grafting
title_full_unstemmed High-sensitivity C-reactive protein (hs-CRP) and tumor necrotizing factor-alpha (TNF-alpha) after on- and off- pump coronary artery bypass grafting
title_short High-sensitivity C-reactive protein (hs-CRP) and tumor necrotizing factor-alpha (TNF-alpha) after on- and off- pump coronary artery bypass grafting
title_sort high-sensitivity c-reactive protein (hs-crp) and tumor necrotizing factor-alpha (tnf-alpha) after on- and off- pump coronary artery bypass grafting
topic Research-Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484567/
https://www.ncbi.nlm.nih.gov/pubmed/23439767
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