Early and prolonged ECG alterations resembling a myocardial injury after severe amitriptyline poisoning

Evidence of cardiovascular toxicity is present in the majority of tricyclic antidepressant overdoses. We report the case of a 63-year-old woman admitted to our department with a severe amitriptyline poisoning. The ECG at admission showed a pattern mimicking an acute anteroseptal subepicardial infarc...

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Detalles Bibliográficos
Autores principales: Berlot, G, Vergolini, A, Calderan, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDIMES Edizioni Internazionali Srl 2010
Materias:
Case-Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484585/
https://www.ncbi.nlm.nih.gov/pubmed/23441005
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author Berlot, G
Vergolini, A
Calderan, C
author_facet Berlot, G
Vergolini, A
Calderan, C
author_sort Berlot, G
collection PubMed
description Evidence of cardiovascular toxicity is present in the majority of tricyclic antidepressant overdoses. We report the case of a 63-year-old woman admitted to our department with a severe amitriptyline poisoning. The ECG at admission showed a pattern mimicking an acute anteroseptal subepicardial infarction. This pattern persisted for 11 days. Myocardial enzymes and echocardiographic findings never confirmed an ischemic event. At discharge, the ECG returned normal without cardiac or neurologic sequelae. Our experience suggest that after severe tricyclic antidepressant ingestion, ECG alterations resembling myocardial injury may occur early and last for a longer period than previously reported.
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spelling pubmed-34845852013-02-25 Early and prolonged ECG alterations resembling a myocardial injury after severe amitriptyline poisoning Berlot, G Vergolini, A Calderan, C HSR Proc Intensive Care Cardiovasc Anesth Case-Report Evidence of cardiovascular toxicity is present in the majority of tricyclic antidepressant overdoses. We report the case of a 63-year-old woman admitted to our department with a severe amitriptyline poisoning. The ECG at admission showed a pattern mimicking an acute anteroseptal subepicardial infarction. This pattern persisted for 11 days. Myocardial enzymes and echocardiographic findings never confirmed an ischemic event. At discharge, the ECG returned normal without cardiac or neurologic sequelae. Our experience suggest that after severe tricyclic antidepressant ingestion, ECG alterations resembling myocardial injury may occur early and last for a longer period than previously reported. EDIMES Edizioni Internazionali Srl 2010 /pmc/articles/PMC3484585/ /pubmed/23441005 Text en Copyright © 2010, HSR Proceedings in Intensive Care and Cardiovascular Anesthesia http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License 3.0, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. See: http://creativecommons.org/licenses/by-nc/3.0/ and http://creativecommons.org/licenses/by-nc/3.0/legalcode.
spellingShingle Case-Report
Berlot, G
Vergolini, A
Calderan, C
Early and prolonged ECG alterations resembling a myocardial injury after severe amitriptyline poisoning
title Early and prolonged ECG alterations resembling a myocardial injury after severe amitriptyline poisoning
title_full Early and prolonged ECG alterations resembling a myocardial injury after severe amitriptyline poisoning
title_fullStr Early and prolonged ECG alterations resembling a myocardial injury after severe amitriptyline poisoning
title_full_unstemmed Early and prolonged ECG alterations resembling a myocardial injury after severe amitriptyline poisoning
title_short Early and prolonged ECG alterations resembling a myocardial injury after severe amitriptyline poisoning
title_sort early and prolonged ecg alterations resembling a myocardial injury after severe amitriptyline poisoning
topic Case-Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484585/
https://www.ncbi.nlm.nih.gov/pubmed/23441005
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AT calderanc earlyandprolongedecgalterationsresemblingamyocardialinjuryaftersevereamitriptylinepoisoning

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