Post cardiac arrest therapeutic hypothermia in adult patients, state of art and practical considerations

The importance of therapeutic hypothermia in selected categories of patients has been widely demonstrated. Laboratory, animal, and human studies permitted to understand the molecular mechanisms underlying cooling and its importance in preventing the ischemia/reperfusion injury of the brain. The deve...

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Detalles Bibliográficos
Autores principales: Beccaria, P F, Turi, S, Cristofolini, M, Colombo, S, Leggieri, C, Vinciguerra, F, Zangrillo, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDIMES Edizioni Internazionali Srl 2010
Materias:
Review-Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484613/
https://www.ncbi.nlm.nih.gov/pubmed/23440518
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author Beccaria, P F
Turi, S
Cristofolini, M
Colombo, S
Leggieri, C
Vinciguerra, F
Zangrillo, A
author_facet Beccaria, P F
Turi, S
Cristofolini, M
Colombo, S
Leggieri, C
Vinciguerra, F
Zangrillo, A
author_sort Beccaria, P F
collection PubMed
description The importance of therapeutic hypothermia in selected categories of patients has been widely demonstrated. Laboratory, animal, and human studies permitted to understand the molecular mechanisms underlying cooling and its importance in preventing the ischemia/reperfusion injury of the brain. The development of new technologies offered the possibility to reach the desired temperature effectively and rapidly, reducing related side effects. Nevertheless, the application of systematic protocols of cooling has not been adequately reached in many hospitals. In this paper the most recent findings regarding hypothermia, its physiological bases and ways of application are reviewed.
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spelling pubmed-34846132013-02-25 Post cardiac arrest therapeutic hypothermia in adult patients, state of art and practical considerations Beccaria, P F Turi, S Cristofolini, M Colombo, S Leggieri, C Vinciguerra, F Zangrillo, A HSR Proc Intensive Care Cardiovasc Anesth Review-Article The importance of therapeutic hypothermia in selected categories of patients has been widely demonstrated. Laboratory, animal, and human studies permitted to understand the molecular mechanisms underlying cooling and its importance in preventing the ischemia/reperfusion injury of the brain. The development of new technologies offered the possibility to reach the desired temperature effectively and rapidly, reducing related side effects. Nevertheless, the application of systematic protocols of cooling has not been adequately reached in many hospitals. In this paper the most recent findings regarding hypothermia, its physiological bases and ways of application are reviewed. EDIMES Edizioni Internazionali Srl 2010 /pmc/articles/PMC3484613/ /pubmed/23440518 Text en Copyright © 2010, HSR Proceedings in Intensive Care and Cardiovascular Anesthesia http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License 3.0, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. See: http://creativecommons.org/licenses/by-nc/3.0/ and http://creativecommons.org/licenses/by-nc/3.0/legalcode.
spellingShingle Review-Article
Beccaria, P F
Turi, S
Cristofolini, M
Colombo, S
Leggieri, C
Vinciguerra, F
Zangrillo, A
Post cardiac arrest therapeutic hypothermia in adult patients, state of art and practical considerations
title Post cardiac arrest therapeutic hypothermia in adult patients, state of art and practical considerations
title_full Post cardiac arrest therapeutic hypothermia in adult patients, state of art and practical considerations
title_fullStr Post cardiac arrest therapeutic hypothermia in adult patients, state of art and practical considerations
title_full_unstemmed Post cardiac arrest therapeutic hypothermia in adult patients, state of art and practical considerations
title_short Post cardiac arrest therapeutic hypothermia in adult patients, state of art and practical considerations
title_sort post cardiac arrest therapeutic hypothermia in adult patients, state of art and practical considerations
topic Review-Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484613/
https://www.ncbi.nlm.nih.gov/pubmed/23440518
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