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Alteration in respiratory physiology in obesity for anesthesia-critical care physician

Obesity is known to be a major risk factor of a whole range of cardiovascular, metabolic and respiratory disorders. The pattern of regional fat distribution plays an important role in the pre-disposition of obese subjects to respiratory complications. Obesity is responsible for important changes in...

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Autores principales: Porhomayon, J, Papadakos, P, Singh, A, Nader, N D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDIMES Edizioni Internazionali Srl 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484623/
https://www.ncbi.nlm.nih.gov/pubmed/23439281
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author Porhomayon, J
Papadakos, P
Singh, A
Nader, N D
author_facet Porhomayon, J
Papadakos, P
Singh, A
Nader, N D
author_sort Porhomayon, J
collection PubMed
description Obesity is known to be a major risk factor of a whole range of cardiovascular, metabolic and respiratory disorders. The pattern of regional fat distribution plays an important role in the pre-disposition of obese subjects to respiratory complications. Obesity is responsible for important changes in respiratory function both during spontaneous breathing as well as during general anesthesia and mechanical ventilation. The most characteristic abnormalities consist of decreased functional residual capacity, reduced expiratory reserve volume, decreased compliance and increased resistance of the respiratory system. Breathing at low lung volume promotes airway closure in the dependent lung zones with consequent gas exchange abnormalities even though lung carbon monoxide-diffusing capacity is normal or increased. Weight loss can reduce many of the alterations in pulmonary function related to obesity.
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spelling pubmed-34846232013-02-25 Alteration in respiratory physiology in obesity for anesthesia-critical care physician Porhomayon, J Papadakos, P Singh, A Nader, N D HSR Proc Intensive Care Cardiovasc Anesth Review-Article Obesity is known to be a major risk factor of a whole range of cardiovascular, metabolic and respiratory disorders. The pattern of regional fat distribution plays an important role in the pre-disposition of obese subjects to respiratory complications. Obesity is responsible for important changes in respiratory function both during spontaneous breathing as well as during general anesthesia and mechanical ventilation. The most characteristic abnormalities consist of decreased functional residual capacity, reduced expiratory reserve volume, decreased compliance and increased resistance of the respiratory system. Breathing at low lung volume promotes airway closure in the dependent lung zones with consequent gas exchange abnormalities even though lung carbon monoxide-diffusing capacity is normal or increased. Weight loss can reduce many of the alterations in pulmonary function related to obesity. EDIMES Edizioni Internazionali Srl 2011 /pmc/articles/PMC3484623/ /pubmed/23439281 Text en Copyright © 2011, HSR Proceedings in Intensive Care and Cardiovascular Anesthesia http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License 3.0, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license.See: http://creativecommons.org/licenses/by-nc/3.0/ and http://creativecommons.org/licenses/by-nc/3.0/legalcode. (http://creativecommons.org/licenses/by-nc/3.0/legalcode)
spellingShingle Review-Article
Porhomayon, J
Papadakos, P
Singh, A
Nader, N D
Alteration in respiratory physiology in obesity for anesthesia-critical care physician
title Alteration in respiratory physiology in obesity for anesthesia-critical care physician
title_full Alteration in respiratory physiology in obesity for anesthesia-critical care physician
title_fullStr Alteration in respiratory physiology in obesity for anesthesia-critical care physician
title_full_unstemmed Alteration in respiratory physiology in obesity for anesthesia-critical care physician
title_short Alteration in respiratory physiology in obesity for anesthesia-critical care physician
title_sort alteration in respiratory physiology in obesity for anesthesia-critical care physician
topic Review-Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484623/
https://www.ncbi.nlm.nih.gov/pubmed/23439281
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