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A Forward Genetic Screen Identifies Eukaryotic Translation Initiation Factor 3, Subunit H (eIF3h), as an Enhancer of Variegation in the Mouse

We have used a forward genetic screen to identify genes required for transgene silencing in the mouse. Previously these genes were found using candidate-based sequencing, a slow and labor-intensive process. Recently, whole-exome deep sequencing has accelerated our ability to find the causative point...

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Detalles Bibliográficos
Autores principales:	Daxinger, Lucia, Oey, Harald, Apedaile, Anwyn, Sutton, Joanne, Ashe, Alyson, Whitelaw, Emma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2012
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484669/ https://www.ncbi.nlm.nih.gov/pubmed/23173090 http://dx.doi.org/10.1534/g3.112.004036

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