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Maintaining Sufficient Nanos Is a Critical Function for Polar Granule Component in the Specification of Primordial Germ Cells

Primordial germ cells (PGC) are the precursors of germline stem cells. In Drosophila, PGC specification is thought to require transcriptional quiescence and three genes, polar granule component (pgc), nanos (nos), and germ cell less (gcl) function to downregulate Pol II transcription. While it is no...

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Detalles Bibliográficos
Autores principales:	Deshpande, Girish, Spady, Emma, Goodhouse, Joe, Schedl, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2012
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484670/ https://www.ncbi.nlm.nih.gov/pubmed/23173091 http://dx.doi.org/10.1534/g3.112.004192

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