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Improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda
A 64-year-old Caucasian male complaining of redness and tearing for 3 years in both eyes was referred for evaluation of cicatricial conjunctivitis. Ocular cicatricial pemphigoid was suspected and this diagnosis was confirmed through biopsy. The patient’s condition showed moderate improvement followi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484721/ https://www.ncbi.nlm.nih.gov/pubmed/23118521 http://dx.doi.org/10.2147/OPTH.S35402 |
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author | Ford, R Marshall Khalifa, Yousuf M |
author_facet | Ford, R Marshall Khalifa, Yousuf M |
author_sort | Ford, R Marshall |
collection | PubMed |
description | A 64-year-old Caucasian male complaining of redness and tearing for 3 years in both eyes was referred for evaluation of cicatricial conjunctivitis. Ocular cicatricial pemphigoid was suspected and this diagnosis was confirmed through biopsy. The patient’s condition showed moderate improvement following treatment with methotrexate and mycophenolate mofetil. The patient was later diagnosed with porphyria cutanea tarda and phlebotomy treatments were subsequently initiated. The patient’s ocular symptoms improved further after he began receiving these phlebotomy treatments, and conventional treatment was discontinued. The authors hypothesize that circulating porphyrins activated by ultraviolet light could be the cause of the ocular cicatricial pemphigoid in this patient. |
format | Online Article Text |
id | pubmed-3484721 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-34847212012-11-01 Improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda Ford, R Marshall Khalifa, Yousuf M Clin Ophthalmol Case Report A 64-year-old Caucasian male complaining of redness and tearing for 3 years in both eyes was referred for evaluation of cicatricial conjunctivitis. Ocular cicatricial pemphigoid was suspected and this diagnosis was confirmed through biopsy. The patient’s condition showed moderate improvement following treatment with methotrexate and mycophenolate mofetil. The patient was later diagnosed with porphyria cutanea tarda and phlebotomy treatments were subsequently initiated. The patient’s ocular symptoms improved further after he began receiving these phlebotomy treatments, and conventional treatment was discontinued. The authors hypothesize that circulating porphyrins activated by ultraviolet light could be the cause of the ocular cicatricial pemphigoid in this patient. Dove Medical Press 2012 2012-10-24 /pmc/articles/PMC3484721/ /pubmed/23118521 http://dx.doi.org/10.2147/OPTH.S35402 Text en © 2012 Ford and Khalifa, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. |
spellingShingle | Case Report Ford, R Marshall Khalifa, Yousuf M Improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda |
title | Improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda |
title_full | Improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda |
title_fullStr | Improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda |
title_full_unstemmed | Improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda |
title_short | Improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda |
title_sort | improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484721/ https://www.ncbi.nlm.nih.gov/pubmed/23118521 http://dx.doi.org/10.2147/OPTH.S35402 |
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