Myotubular myopathy and the neuromuscular junction: a novel therapeutic approach from mouse models

Myotubular myopathy (MTM) is a severe congenital muscle disease characterized by profound weakness, early respiratory failure and premature lethality. MTM is defined by muscle biopsy findings that include centralized nuclei and disorganization of perinuclear organelles. No treatments currently exist...

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Detalles Bibliográficos
Autores principales: Dowling, James J., Joubert, Romain, Low, Sean E., Durban, Ashley N., Messaddeq, Nadia, Li, Xingli, Dulin-Smith, Ashley N., Snyder, Andrew D., Marshall, Morgan L., Marshall, Jordan T., Beggs, Alan H., Buj-Bello, Anna, Pierson, Christopher R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484867/
https://www.ncbi.nlm.nih.gov/pubmed/22645112
http://dx.doi.org/10.1242/dmm.009746

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