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Perturbations in Histidine Biosynthesis Uncover Robustness in the Metabolic Network of Salmonella enterica

Phosphoribosylamine (PRA) is an intermediate in the biosynthetic pathway that is common to thiamine and purines. Glutamine phosphoribosyl pyrophosphate (PRPP) amidotransferase is the product of the purF gene in Salmonella enterica and catalyzes the synthesis of PRA from PRPP and glutamine. Strains l...

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Detalles Bibliográficos
Autores principales:	Koenigsknecht, Mark J., Lambrecht, Jennifer A., Fenlon, Luke A., Downs, Diana M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485032/ https://www.ncbi.nlm.nih.gov/pubmed/23133571 http://dx.doi.org/10.1371/journal.pone.0048207

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