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Immunogenicity of a Fusion Protein Containing Immunodominant Epitopes of Ag85C, MPT51, and HspX from Mycobacterium tuberculosis in Mice and Active TB Infection
Tuberculosis (TB) remains a major global health problem. The only vaccine against tuberculosis, attenuated Mycobacterium bovis Bacillus Calmette-Guerin (BCG), has demonstrated relatively low efficacy and does not provide satisfactory protection against the disease in adults. More effective vaccines...
Autores principales: | de Sousa, Eduardo Martins, da Costa, Adeliane Castro, Trentini, Monalisa Martins, de Araújo Filho, João Alves, Kipnis, André, Junqueira-Kipnis, Ana Paula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485045/ https://www.ncbi.nlm.nih.gov/pubmed/23133523 http://dx.doi.org/10.1371/journal.pone.0047781 |
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