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Prevalence and Factors Associated with Hepatitis B Immunization and Infection among Men Who Have Sex with Men in Beijing, China

BACKGROUND: Among the Chinese population of 1.3 billion, there are an estimated 93 million carriers of hepatitis B virus (HBV). Men who have sex with men (MSM) are at increased risk for HBV infection; however, the prevalence of HBV immunization and infection among Chinese MSM remains undetermined. M...

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Autores principales: Wang, Chao, Wang, YouXin, Huang, XiaoJie, Li, Xia, Zhang, Tong, Song, ManShu, Wu, LiJuan, Du, Juan, Lu, XiaoQin, Shao, Shuang, Zhao, FeiFei, Ball, Michele A., Wu, Hao, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485055/
https://www.ncbi.nlm.nih.gov/pubmed/23133573
http://dx.doi.org/10.1371/journal.pone.0048219
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author Wang, Chao
Wang, YouXin
Huang, XiaoJie
Li, Xia
Zhang, Tong
Song, ManShu
Wu, LiJuan
Du, Juan
Lu, XiaoQin
Shao, Shuang
Zhao, FeiFei
Ball, Michele A.
Wu, Hao
Wang, Wei
author_facet Wang, Chao
Wang, YouXin
Huang, XiaoJie
Li, Xia
Zhang, Tong
Song, ManShu
Wu, LiJuan
Du, Juan
Lu, XiaoQin
Shao, Shuang
Zhao, FeiFei
Ball, Michele A.
Wu, Hao
Wang, Wei
author_sort Wang, Chao
collection PubMed
description BACKGROUND: Among the Chinese population of 1.3 billion, there are an estimated 93 million carriers of hepatitis B virus (HBV). Men who have sex with men (MSM) are at increased risk for HBV infection; however, the prevalence of HBV immunization and infection among Chinese MSM remains undetermined. METHODS: A cross-sectional survey of 1,114 eligible participants was conducted in Beijing, China. Multiple methods were used to recruit study participants. Demographic information and potential correlated factors were collected by questionnaire. Additionally, blood specimens were collected and tested for sexually transmitted infections and serologic markers of hepatitis B immunization and infection. RESULTS: Laboratory data were available for 1,111 participants (99.7%), the prevalence of hepatitis B immunization was 38.9%, and 26.5% had serologic markers of HBV infection. Multivariate analyses indicated that higher education level, smaller number of male sex partners in the past 12 months, reported diagnosis of sexually transmitted disease (STD), and history of blood donation were independently associated with HBV immunization. Absence of steady male sex partner(s) in the past 12 months, and reported diagnosis of STD were shown to be independently associated with HBV infection. MSM positive for HBV infection were more likely to have past or current syphilis infection. CONCLUSIONS: Low prevalence of HBV immunization and high prevalence of HBV infection among Chinese MSM and a correlation between sexual risk factors and hepatitis B infection indicate that comprehensive preventative measures for HBV among MSM, including blood donor and HIV-STD clinic vaccination programs as well as targeted health education campaigns should be developed in China.
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spelling pubmed-34850552012-11-06 Prevalence and Factors Associated with Hepatitis B Immunization and Infection among Men Who Have Sex with Men in Beijing, China Wang, Chao Wang, YouXin Huang, XiaoJie Li, Xia Zhang, Tong Song, ManShu Wu, LiJuan Du, Juan Lu, XiaoQin Shao, Shuang Zhao, FeiFei Ball, Michele A. Wu, Hao Wang, Wei PLoS One Research Article BACKGROUND: Among the Chinese population of 1.3 billion, there are an estimated 93 million carriers of hepatitis B virus (HBV). Men who have sex with men (MSM) are at increased risk for HBV infection; however, the prevalence of HBV immunization and infection among Chinese MSM remains undetermined. METHODS: A cross-sectional survey of 1,114 eligible participants was conducted in Beijing, China. Multiple methods were used to recruit study participants. Demographic information and potential correlated factors were collected by questionnaire. Additionally, blood specimens were collected and tested for sexually transmitted infections and serologic markers of hepatitis B immunization and infection. RESULTS: Laboratory data were available for 1,111 participants (99.7%), the prevalence of hepatitis B immunization was 38.9%, and 26.5% had serologic markers of HBV infection. Multivariate analyses indicated that higher education level, smaller number of male sex partners in the past 12 months, reported diagnosis of sexually transmitted disease (STD), and history of blood donation were independently associated with HBV immunization. Absence of steady male sex partner(s) in the past 12 months, and reported diagnosis of STD were shown to be independently associated with HBV infection. MSM positive for HBV infection were more likely to have past or current syphilis infection. CONCLUSIONS: Low prevalence of HBV immunization and high prevalence of HBV infection among Chinese MSM and a correlation between sexual risk factors and hepatitis B infection indicate that comprehensive preventative measures for HBV among MSM, including blood donor and HIV-STD clinic vaccination programs as well as targeted health education campaigns should be developed in China. Public Library of Science 2012-10-25 /pmc/articles/PMC3485055/ /pubmed/23133573 http://dx.doi.org/10.1371/journal.pone.0048219 Text en © 2012 Wang et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Wang, Chao
Wang, YouXin
Huang, XiaoJie
Li, Xia
Zhang, Tong
Song, ManShu
Wu, LiJuan
Du, Juan
Lu, XiaoQin
Shao, Shuang
Zhao, FeiFei
Ball, Michele A.
Wu, Hao
Wang, Wei
Prevalence and Factors Associated with Hepatitis B Immunization and Infection among Men Who Have Sex with Men in Beijing, China
title Prevalence and Factors Associated with Hepatitis B Immunization and Infection among Men Who Have Sex with Men in Beijing, China
title_full Prevalence and Factors Associated with Hepatitis B Immunization and Infection among Men Who Have Sex with Men in Beijing, China
title_fullStr Prevalence and Factors Associated with Hepatitis B Immunization and Infection among Men Who Have Sex with Men in Beijing, China
title_full_unstemmed Prevalence and Factors Associated with Hepatitis B Immunization and Infection among Men Who Have Sex with Men in Beijing, China
title_short Prevalence and Factors Associated with Hepatitis B Immunization and Infection among Men Who Have Sex with Men in Beijing, China
title_sort prevalence and factors associated with hepatitis b immunization and infection among men who have sex with men in beijing, china
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485055/
https://www.ncbi.nlm.nih.gov/pubmed/23133573
http://dx.doi.org/10.1371/journal.pone.0048219
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