Harvesting and Cryo-cooling Crystals of Membrane Proteins Grown in Lipidic Mesophases for Structure Determination by Macromolecular Crystallography

An important route to understanding how proteins function at a mechanistic level is to have the structure of the target protein available, ideally at atomic resolution. Presently, there is only one way to capture such information as applied to integral membrane proteins (Figure 1), and the complexes...

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Detalles Bibliográficos
Autores principales: Li, Dianfan, Boland, Coilín, Aragao, David, Walsh, Kilian, Caffrey, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2012
Materias:
Materials Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485064/
https://www.ncbi.nlm.nih.gov/pubmed/22971942
http://dx.doi.org/10.3791/4001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485064/
https://www.ncbi.nlm.nih.gov/pubmed/22971942
http://dx.doi.org/10.3791/4001

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