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Specification, annotation, visualization and simulation of a large rule-based model for ERBB receptor signaling

BACKGROUND: Mathematical/computational models are needed to understand cell signaling networks, which are complex. Signaling proteins contain multiple functional components and multiple sites of post-translational modification. The multiplicity of components and sites of modification ensures that in...

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Detalles Bibliográficos
Autores principales:	Creamer, Matthew S, Stites, Edward C, Aziz, Meraj, Cahill, James A, Tan, Chin Wee, Berens, Michael E, Han, Haiyong, Bussey, Kimberley J, Von Hoff, Daniel D, Hlavacek, William S, Posner, Richard G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485121/ https://www.ncbi.nlm.nih.gov/pubmed/22913808 http://dx.doi.org/10.1186/1752-0509-6-107

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