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Regional Variation in Aortic AT1b Receptor mRNA Abundance Is Associated with Contractility but Unrelated to Atherosclerosis and Aortic Aneurysms
BACKGROUND: Angiotensin II (AngII), the main bioactive peptide of the renin angiotensin system, exerts most of its biological actions through stimulation of AngII type 1 (AT1) receptors. This receptor is expressed as 2 structurally similar subtypes in rodents, termed AT1a and AT1b. Although AT1a rec...
Autores principales: | Poduri, Aruna, Owens, A. Phillip, Howatt, Deborah A., Moorleghen, Jessica J., Balakrishnan, Anju, Cassis, Lisa A., Daugherty, Alan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485205/ https://www.ncbi.nlm.nih.gov/pubmed/23119030 http://dx.doi.org/10.1371/journal.pone.0048462 |
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