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Scaffold-Based Pan-Agonist Design for the PPARα, PPARβ and PPARγ Receptors
As important members of nuclear receptor superfamily, Peroxisome proliferator-activated receptors (PPAR) play essential roles in regulating cellular differentiation, development, metabolism, and tumorigenesis of higher organisms. The PPAR receptors have 3 identified subtypes: PPARα, PPARβ and PPARγ,...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485212/ https://www.ncbi.nlm.nih.gov/pubmed/23119024 http://dx.doi.org/10.1371/journal.pone.0048453 |