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Src-Mediated Cross-Talk between Farnesoid X and Epidermal Growth Factor Receptors Inhibits Human Intestinal Cell Proliferation and Tumorigenesis

Besides its essential role in controlling bile acid and lipid metabolism, the farnesoid X receptor (FXR) protects against intestinal tumorigenesis by promoting apoptosis and inhibiting cell proliferation. However, the mechanisms underlying these anti-proliferative actions of FXR remain to be elucida...

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Detalles Bibliográficos
Autores principales:	Peng, Zhongsheng, Raufman, Jean-Pierre, Xie, Guofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485230/ https://www.ncbi.nlm.nih.gov/pubmed/23119029 http://dx.doi.org/10.1371/journal.pone.0048461

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