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Fasudil Protects the Heart against Ischemia-Reperfusion Injury by Attenuating Endoplasmic Reticulum Stress and Modulating SERCA Activity: The Differential Role for PI3K/Akt and JAK2/STAT3 Signaling Pathways

Disordered calcium homeostasis can lead to endoplasmic reticulum (ER) stress. Our previous data showed that time course activation of ER stress contributes to time-related increase in ischemia-reperfusion (I/R) injury. However, it has not been tested whether PI3K/Akt and JAK2/STAT3 pathways play dif...

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Detalles Bibliográficos
Autores principales:	Li, Yapeng, Zhu, Wei, Tao, Jianping, Xin, Ping, Liu, Mingya, Li, Jingbo, Wei, Meng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485283/ https://www.ncbi.nlm.nih.gov/pubmed/23118936 http://dx.doi.org/10.1371/journal.pone.0048115

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