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C. difficile 630Δerm Spo0A Regulates Sporulation, but Does Not Contribute to Toxin Production, by Direct High-Affinity Binding to Target DNA
Clostridium difficile is a Gram positive, anaerobic bacterium that can form highly resistant endospores. The bacterium is the causative agent of C. difficile infection (CDI), for which the symptoms can range from a mild diarrhea to potentially fatal pseudomembranous colitis and toxic megacolon. Endo...
Autores principales: | Rosenbusch, Katharina E., Bakker, Dennis, Kuijper, Ed J., Smits, Wiep Klaas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485338/ https://www.ncbi.nlm.nih.gov/pubmed/23119071 http://dx.doi.org/10.1371/journal.pone.0048608 |
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