Cargando…

Maternal Vitamin C Deficiency during Pregnancy Persistently Impairs Hippocampal Neurogenesis in Offspring of Guinea Pigs

While having the highest vitamin C (VitC) concentrations in the body, specific functions of VitC in the brain have only recently been acknowledged. We have shown that postnatal VitC deficiency in guinea pigs causes impairment of hippocampal memory function and leads to 30% less neurons. This study i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tveden-Nyborg, Pernille, Vogt, Lucile, Schjoldager, Janne G., Jeannet, Natalie, Hasselholt, Stine, Paidi, Maya D., Christen, Stephan, Lykkesfeldt, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485340/ https://www.ncbi.nlm.nih.gov/pubmed/23119033 http://dx.doi.org/10.1371/journal.pone.0048488

Ejemplares similares

Prenatal vitamin C deficiency results in differential levels of oxidative stress during late gestation in foetal guinea pig brains
por: Paidi, Maya D., et al.
Publicado: (2014)

Chronic Vitamin C Deficiency Promotes Redox Imbalance in the Brain but Does Not Alter Sodium-Dependent Vitamin C Transporter 2 Expression
por: Paidi, Maya D., et al.
Publicado: (2014)

Early Life Vitamin C Deficiency Does Not Alter Morphology of Hippocampal CA1 Pyramidal Neurons or Markers of Synaptic Plasticity in a Guinea Pig Model
por: Hansen, Stine N., et al.
Publicado: (2018)

l-dehydroascorbic acid can substitute l-ascorbic acid as dietary vitamin C source in guinea pigs
por: Frikke-Schmidt, Henriette, et al.
Publicado: (2015)

Vitamin C Deficiency Reduces Muscarinic Receptor Coronary Artery Vasoconstriction and Plasma Tetrahydrobiopterin Concentration in Guinea Pigs
por: Skovsted, Gry Freja, et al.
Publicado: (2017)

The development of nonalcoholic steatohepatitis is subjected to breeder dependent variation in guinea pigs
por: Ipsen, D. H., et al.
Publicado: (2021)

Dietary Long-Chain Fatty Acids Accelerate Metabolic Dysfunction in Guinea Pigs with Non-Alcoholic Steatohepatitis
por: Pedersen, Kamilla, et al.
Publicado: (2023)

Modelling Nonalcoholic Steatohepatitis In Vivo—A Close Transcriptomic Similarity Supports the Guinea Pig Disease Model
por: Skat-Rørdam, Josephine, et al.
Publicado: (2021)

Does Vitamin C Deficiency Affect Cognitive Development and Function?
por: Hansen, Stine Normann, et al.
Publicado: (2014)

Vitamin C Deficiency Exacerbates Dysfunction of Atherosclerotic Coronary Arteries in Guinea Pigs Fed a High-Fat Diet
por: Skovsted, Gry Freja, et al.
Publicado: (2022)

Vitamin C Deficiency May Delay Diet-Induced NASH Regression in the Guinea Pig
por: Skat-Rørdam, Josephine, et al.
Publicado: (2021)

The Pharmacokinetics of Vitamin C
por: Lykkesfeldt, Jens, et al.
Publicado: (2019)

Atorvastatin and Vitamin E Accelerates NASH Resolution by Dietary Intervention in a Preclinical Guinea Pig Model
por: Klaebel, Julie Hviid, et al.
Publicado: (2019)

High-fat but not sucrose intake is essential for induction of dyslipidemia and non-alcoholic steatohepatitis in guinea pigs
por: Ipsen, David Højland, et al.
Publicado: (2016)

Regulation of Vitamin C Homeostasis during Deficiency
por: Lindblad, Maiken, et al.
Publicado: (2013)

Spatial Memory Dysfunction Induced by Vitamin C Deficiency Is Associated with Changes in Monoaminergic Neurotransmitters and Aberrant Synapse Formation
por: Hansen, Stine Normann, et al.
Publicado: (2018)

Does Vitamin C Deficiency Promote Fatty Liver Disease Development?
por: Ipsen, David Højland, et al.
Publicado: (2014)

Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease
por: Ipsen, David Højland, et al.
Publicado: (2018)

Pregnancy Promotes Maternal Hippocampal Neurogenesis in Guinea Pigs
por: Wan, Lily, et al.
Publicado: (2019)

A role of peroxisome proliferator‐activated receptor γ in non‐alcoholic fatty liver disease
por: Skat‐Rørdam, Josephine, et al.
Publicado: (2019)

Dietary Intervention Accelerates NASH Resolution Depending on Inflammatory Status with Minor Additive Effects on Hepatic Injury by Vitamin E Supplementation
por: Klaebel, Julie Hviid, et al.
Publicado: (2020)

Vitamin C Deficiency in the Young Brain—Findings from Experimental Animal Models †
por: Tveden-Nyborg, Pernille
Publicado: (2021)

Differential Effects of Dietary Components on Glucose Intolerance and Non-Alcoholic Steatohepatitis
por: Skat-Rørdam, Josephine, et al.
Publicado: (2021)

Extracellular Vesicles as Drivers of Non-Alcoholic Fatty Liver Disease: Small Particles with Big Impact
por: Ipsen, David Højland, et al.
Publicado: (2021)

Extracranial (125)I Seed Implantation Allows Non-invasive Stereotactic Radioablation of Hippocampal Adult Neurogenesis in Guinea Pigs
por: Wan, Lily, et al.
Publicado: (2021)

Hepatic Stellate Cell Activation and Inactivation in NASH-Fibrosis—Roles as Putative Treatment Targets?
por: Zisser, Alexandra, et al.
Publicado: (2021)

A Long-Term Energy-Rich Diet Increases Prefrontal BDNF in Sprague-Dawley Rats
por: Virtuoso, Alessandro, et al.
Publicado: (2021)

Non-immunogenic Induced Pluripotent Stem Cells, a Promising Way Forward for Allogenic Transplantations for Neurological Disorders
por: Frederiksen, Henriette Reventlow, et al.
Publicado: (2021)

Testosterone is involved in mediating the effects of prenatal stress in male guinea pig offspring
por: Kapoor, Amita, et al.
Publicado: (2011)

Developmental Differences in Neocortex Neurogenesis and Maturation Between the Altricial Dwarf Rabbit and Precocial Guinea Pig
por: Kalusa, Mirjam, et al.
Publicado: (2021)

The maternal social environment shapes offspring growth, physiology, and behavioural phenotype in guinea pigs
por: von Engelhardt, Nikolaus, et al.
Publicado: (2015)

Reduced neural progenitor cell count and cortical neurogenesis in guinea pigs congenitally infected with Toxoplasma gondii
por: Grochow, Thomas, et al.
Publicado: (2023)

Maternal Nicotine Exposure During Gestation and Lactation Period Affects Behavior and Hippocampal Neurogenesis in Mouse Offspring
por: Liu, Fei, et al.
Publicado: (2020)

Guinea Pigs
Publicado: (2013)

GUINEA PIGS
por: Riggs, Shannon M.
Publicado: (2009)

Genetic control of hippocampal neurogenesis
por: Pozniak, Christine D, et al.
Publicado: (2006)

Vocal mother-offspring communication in guinea pigs: females adjust maternal responsiveness to litter size
por: Kober, Melanie, et al.
Publicado: (2008)

Effects of Maternal Hypoxia during Pregnancy on Bone Development in Offspring: A Guinea Pig Model
por: Lee, Alice M. C., et al.
Publicado: (2014)

The sodium current underlying action potentials in guinea pig hippocampal CA1 neurons
Publicado: (1988)

A new age in understanding adult hippocampal neurogenesis in Alzheimer’s disease
por: Hanspal, Maya A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_d8odsl98gt6816j2c6rorrothu