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Pericentromeric Regions Are Refractory To Prompt Repair after Replication Stress-Induced Breakage in HPV16 E6E7-Expressing Epithelial Cells

Chromosomal instability is the major form of genomic instability in cancer cells. Amongst various forms of chromosomal instability, pericentromeric or centromeric instability remains particularly poorly understood. In the present study, we found that pericentromeric instability, evidenced by dynamic...

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Detalles Bibliográficos
Autores principales: Deng, Wen, Tsao, Sai Wah, Guan, Xin-Yuan, Cheung, Annie L. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485353/
https://www.ncbi.nlm.nih.gov/pubmed/23119062
http://dx.doi.org/10.1371/journal.pone.0048576