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CYP24A1 Exacerbated Activity during Diabetes Contributes to Kidney Tubular Apoptosis via Caspase-3 Increased Expression and Activation
Decreases in circulating 25,hydroxyl-vitamin D3 (25 OH D3) and 1,25,dihydroxyl-vitamin D3 (1,25 (OH)2 D3) have been extensively documented in patients with type 2 diabetes. Nevertheless, the molecular reasons behind this drop, and whether it is a cause or an effect of disease progression is still po...
Autores principales: | Tourigny, Alexandre, Charbonneau, Frédrick, Xing, Paul, Boukrab, Rania, Rousseau, Guy, St-Arnaud, René, Brezniceanu, Marie-Luise |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485377/ https://www.ncbi.nlm.nih.gov/pubmed/23119081 http://dx.doi.org/10.1371/journal.pone.0048652 |
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