Unique mitochondrial DNA in highly inbred feral cattle

The Chillingham herd of wild Northumbrian cattle remains viable despite over 300 years of in-breeding and a near-homozygous nuclear genome. Here we report the complete mitochondrial DNA sequence using ultra-deep next generation sequencing. Random population sampling of ~ 10% of the extant herd ident...

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Detalles Bibliográficos
Autores principales: Hudson, Gavin, Wilson, Ian, Payne, Brendan I.A., Elson, Joanna, Samuels, David C., Santibanez-Korev, Mauro, Hall, Stephen J.G., Chinnery, Patrick F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2012
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485552/
https://www.ncbi.nlm.nih.gov/pubmed/22609322
http://dx.doi.org/10.1016/j.mito.2012.05.003
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author Hudson, Gavin
Wilson, Ian
Payne, Brendan I.A.
Elson, Joanna
Samuels, David C.
Santibanez-Korev, Mauro
Hall, Stephen J.G.
Chinnery, Patrick F.
author_facet Hudson, Gavin
Wilson, Ian
Payne, Brendan I.A.
Elson, Joanna
Samuels, David C.
Santibanez-Korev, Mauro
Hall, Stephen J.G.
Chinnery, Patrick F.
author_sort Hudson, Gavin
collection PubMed
description The Chillingham herd of wild Northumbrian cattle remains viable despite over 300 years of in-breeding and a near-homozygous nuclear genome. Here we report the complete mitochondrial DNA sequence using ultra-deep next generation sequencing. Random population sampling of ~ 10% of the extant herd identified a single mtDNA haplotype harbouring a unique bovine variant present in all other higher mammals (m.11789C/Y421H) which may contribute to their survival.
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spelling pubmed-34855522012-12-04 Unique mitochondrial DNA in highly inbred feral cattle Hudson, Gavin Wilson, Ian Payne, Brendan I.A. Elson, Joanna Samuels, David C. Santibanez-Korev, Mauro Hall, Stephen J.G. Chinnery, Patrick F. Mitochondrion Short Communication The Chillingham herd of wild Northumbrian cattle remains viable despite over 300 years of in-breeding and a near-homozygous nuclear genome. Here we report the complete mitochondrial DNA sequence using ultra-deep next generation sequencing. Random population sampling of ~ 10% of the extant herd identified a single mtDNA haplotype harbouring a unique bovine variant present in all other higher mammals (m.11789C/Y421H) which may contribute to their survival. Elsevier Science 2012-07 /pmc/articles/PMC3485552/ /pubmed/22609322 http://dx.doi.org/10.1016/j.mito.2012.05.003 Text en © 2012 Elsevier B.V. https://creativecommons.org/licenses/by/3.0/ Open Access under CC BY 3.0 (https://creativecommons.org/licenses/by/3.0/) license
spellingShingle Short Communication
Hudson, Gavin
Wilson, Ian
Payne, Brendan I.A.
Elson, Joanna
Samuels, David C.
Santibanez-Korev, Mauro
Hall, Stephen J.G.
Chinnery, Patrick F.
Unique mitochondrial DNA in highly inbred feral cattle
title Unique mitochondrial DNA in highly inbred feral cattle
title_full Unique mitochondrial DNA in highly inbred feral cattle
title_fullStr Unique mitochondrial DNA in highly inbred feral cattle
title_full_unstemmed Unique mitochondrial DNA in highly inbred feral cattle
title_short Unique mitochondrial DNA in highly inbred feral cattle
title_sort unique mitochondrial dna in highly inbred feral cattle
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485552/
https://www.ncbi.nlm.nih.gov/pubmed/22609322
http://dx.doi.org/10.1016/j.mito.2012.05.003
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