Conditional over-expression of PITX1 causes skeletal muscle dystrophy in mice

Paired-like homeodomain transcription factor 1 (PITX1) was specifically up-regulated in patients with facioscapulohumeral muscular dystrophy (FSHD) by comparing the genome-wide mRNA expression profiles of 12 neuromuscular disorders. In addition, it is the only known direct transcriptional target of...

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Detalles Bibliográficos
Autores principales: Pandey, Sachchida N., Cabotage, Jennifer, Shi, Rongye, Dixit, Manjusha, Sutherland, Margret, Liu, Jian, Muger, Stephanie, Harper, Scott Q., Nagaraju, Kanneboyina, Chen, Yi-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486706/
https://www.ncbi.nlm.nih.gov/pubmed/23125914
http://dx.doi.org/10.1242/bio.20121305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486706/
https://www.ncbi.nlm.nih.gov/pubmed/23125914
http://dx.doi.org/10.1242/bio.20121305

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