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Conditional over-expression of PITX1 causes skeletal muscle dystrophy in mice
Paired-like homeodomain transcription factor 1 (PITX1) was specifically up-regulated in patients with facioscapulohumeral muscular dystrophy (FSHD) by comparing the genome-wide mRNA expression profiles of 12 neuromuscular disorders. In addition, it is the only known direct transcriptional target of...
Autores principales: | Pandey, Sachchida N., Cabotage, Jennifer, Shi, Rongye, Dixit, Manjusha, Sutherland, Margret, Liu, Jian, Muger, Stephanie, Harper, Scott Q., Nagaraju, Kanneboyina, Chen, Yi-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486706/ https://www.ncbi.nlm.nih.gov/pubmed/23125914 http://dx.doi.org/10.1242/bio.20121305 |
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