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The HIV-1 Rev Protein Enhances Encapsidation of Unspliced and Spliced, RRE-Containing Lentiviral Vector RNA

BACKGROUND: During the RNA encapsidation process of human immunodeficiency virus (HIV) viral genomic, unspliced RNA (gRNA) is preferentially incorporated into assembling virions. However, a certain amount of spliced viral transcripts can also be detected in viral particles. Recently, we observed tha...

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Detalles Bibliográficos
Autores principales: Grewe, Bastian, Ehrhardt, Katrin, Hoffmann, Bianca, Blissenbach, Maik, Brandt, Sabine, Überla, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486793/
https://www.ncbi.nlm.nih.gov/pubmed/23133650
http://dx.doi.org/10.1371/journal.pone.0048688