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Selective Constraint on the Upstream Open Reading Frames That Overlap with Coding Sequences in Animals
Upstream open reading frames (uORFs) are translational regulatory elements located in 5′ untranslated regions. They can significantly repress the translation of the downstream coding sequences (CDS), and participate in the spatio-temporal regulations of protein translation. Notwithstanding this biol...
Autores principales: | Hsu, Ming-Kung, Chen, Feng-Chi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486843/ https://www.ncbi.nlm.nih.gov/pubmed/23133632 http://dx.doi.org/10.1371/journal.pone.0048413 |
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