Cargando…

Reconstructing the Dynamics of HIV Evolution within Hosts from Serial Deep Sequence Data

At the early stage of infection, human immunodeficiency virus (HIV)-1 predominantly uses the CCR5 coreceptor for host cell entry. The subsequent emergence of HIV variants that use the CXCR4 coreceptor in roughly half of all infections is associated with an accelerated decline of CD4+ T-cells and rat...

Descripción completa

Detalles Bibliográficos
Autores principales: Poon, Art F. Y., Swenson, Luke C., Bunnik, Evelien M., Edo-Matas, Diana, Schuitemaker, Hanneke, van 't Wout, Angélique B., Harrigan, P. Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486858/
https://www.ncbi.nlm.nih.gov/pubmed/23133358
http://dx.doi.org/10.1371/journal.pcbi.1002753