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Theory on the Coupled Stochastic Dynamics of Transcription and Splice-Site Recognition
Eukaryotic genes are typically split into exons that need to be spliced together to form the mature mRNA. The splicing process depends on the dynamics and interactions among transcription by the RNA polymerase II complex (RNAPII) and the spliceosomal complex consisting of multiple small nuclear ribo...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486868/ https://www.ncbi.nlm.nih.gov/pubmed/23133354 http://dx.doi.org/10.1371/journal.pcbi.1002747 |