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Theory on the Coupled Stochastic Dynamics of Transcription and Splice-Site Recognition

Eukaryotic genes are typically split into exons that need to be spliced together to form the mature mRNA. The splicing process depends on the dynamics and interactions among transcription by the RNA polymerase II complex (RNAPII) and the spliceosomal complex consisting of multiple small nuclear ribo...

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Detalles Bibliográficos
Autores principales: Murugan, Rajamanickam, Kreiman, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486868/
https://www.ncbi.nlm.nih.gov/pubmed/23133354
http://dx.doi.org/10.1371/journal.pcbi.1002747