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The First Korean Case Report of Anti-Gerbich
In this study, we report the first Korean case of an anti-Gerbich (Ge) alloantibody to a high-incidence antigen that belongs to the Ge blood group system. The alloantibody was detected in a middle-aged Korean woman who did not have a history of transfusion. Her blood type was B+, and findings from t...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society for Laboratory Medicine
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486941/ https://www.ncbi.nlm.nih.gov/pubmed/23130346 http://dx.doi.org/10.3343/alm.2012.32.6.442 |
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author | Jeon, You La Park, Tae Sung Cho, Sun Young Oh, Seung Hwan Kim, Myeong Hee Kang, So Young Lee, Woo-In |
author_facet | Jeon, You La Park, Tae Sung Cho, Sun Young Oh, Seung Hwan Kim, Myeong Hee Kang, So Young Lee, Woo-In |
author_sort | Jeon, You La |
collection | PubMed |
description | In this study, we report the first Korean case of an anti-Gerbich (Ge) alloantibody to a high-incidence antigen that belongs to the Ge blood group system. The alloantibody was detected in a middle-aged Korean woman who did not have a history of transfusion. Her blood type was B+, and findings from the antibody screening test revealed 1+ reactivity in all panels except the autocontrol. The cross-matching test showed incompatible results with all 5 packed red blood cells. Additional blood type antigen and antibody tests confirmed the anti-Ge alloantibody. While rare, cases of hemolytic transfusion reaction or hemolytic disease in newborns due to anti-Ge have been recently reported in the literature. Therefore, additional further studies on alloantibodies to high-incidence antigens, including anti-Ge, are necessary in the future. |
format | Online Article Text |
id | pubmed-3486941 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | The Korean Society for Laboratory Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-34869412012-11-05 The First Korean Case Report of Anti-Gerbich Jeon, You La Park, Tae Sung Cho, Sun Young Oh, Seung Hwan Kim, Myeong Hee Kang, So Young Lee, Woo-In Ann Lab Med Case Report In this study, we report the first Korean case of an anti-Gerbich (Ge) alloantibody to a high-incidence antigen that belongs to the Ge blood group system. The alloantibody was detected in a middle-aged Korean woman who did not have a history of transfusion. Her blood type was B+, and findings from the antibody screening test revealed 1+ reactivity in all panels except the autocontrol. The cross-matching test showed incompatible results with all 5 packed red blood cells. Additional blood type antigen and antibody tests confirmed the anti-Ge alloantibody. While rare, cases of hemolytic transfusion reaction or hemolytic disease in newborns due to anti-Ge have been recently reported in the literature. Therefore, additional further studies on alloantibodies to high-incidence antigens, including anti-Ge, are necessary in the future. The Korean Society for Laboratory Medicine 2012-11 2012-10-17 /pmc/articles/PMC3486941/ /pubmed/23130346 http://dx.doi.org/10.3343/alm.2012.32.6.442 Text en © The Korean Society for Laboratory Medicine. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Jeon, You La Park, Tae Sung Cho, Sun Young Oh, Seung Hwan Kim, Myeong Hee Kang, So Young Lee, Woo-In The First Korean Case Report of Anti-Gerbich |
title | The First Korean Case Report of Anti-Gerbich |
title_full | The First Korean Case Report of Anti-Gerbich |
title_fullStr | The First Korean Case Report of Anti-Gerbich |
title_full_unstemmed | The First Korean Case Report of Anti-Gerbich |
title_short | The First Korean Case Report of Anti-Gerbich |
title_sort | first korean case report of anti-gerbich |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486941/ https://www.ncbi.nlm.nih.gov/pubmed/23130346 http://dx.doi.org/10.3343/alm.2012.32.6.442 |
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