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The First Korean Case Report of Anti-Gerbich

In this study, we report the first Korean case of an anti-Gerbich (Ge) alloantibody to a high-incidence antigen that belongs to the Ge blood group system. The alloantibody was detected in a middle-aged Korean woman who did not have a history of transfusion. Her blood type was B+, and findings from t...

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Autores principales: Jeon, You La, Park, Tae Sung, Cho, Sun Young, Oh, Seung Hwan, Kim, Myeong Hee, Kang, So Young, Lee, Woo-In
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Laboratory Medicine 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486941/
https://www.ncbi.nlm.nih.gov/pubmed/23130346
http://dx.doi.org/10.3343/alm.2012.32.6.442
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author Jeon, You La
Park, Tae Sung
Cho, Sun Young
Oh, Seung Hwan
Kim, Myeong Hee
Kang, So Young
Lee, Woo-In
author_facet Jeon, You La
Park, Tae Sung
Cho, Sun Young
Oh, Seung Hwan
Kim, Myeong Hee
Kang, So Young
Lee, Woo-In
author_sort Jeon, You La
collection PubMed
description In this study, we report the first Korean case of an anti-Gerbich (Ge) alloantibody to a high-incidence antigen that belongs to the Ge blood group system. The alloantibody was detected in a middle-aged Korean woman who did not have a history of transfusion. Her blood type was B+, and findings from the antibody screening test revealed 1+ reactivity in all panels except the autocontrol. The cross-matching test showed incompatible results with all 5 packed red blood cells. Additional blood type antigen and antibody tests confirmed the anti-Ge alloantibody. While rare, cases of hemolytic transfusion reaction or hemolytic disease in newborns due to anti-Ge have been recently reported in the literature. Therefore, additional further studies on alloantibodies to high-incidence antigens, including anti-Ge, are necessary in the future.
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spelling pubmed-34869412012-11-05 The First Korean Case Report of Anti-Gerbich Jeon, You La Park, Tae Sung Cho, Sun Young Oh, Seung Hwan Kim, Myeong Hee Kang, So Young Lee, Woo-In Ann Lab Med Case Report In this study, we report the first Korean case of an anti-Gerbich (Ge) alloantibody to a high-incidence antigen that belongs to the Ge blood group system. The alloantibody was detected in a middle-aged Korean woman who did not have a history of transfusion. Her blood type was B+, and findings from the antibody screening test revealed 1+ reactivity in all panels except the autocontrol. The cross-matching test showed incompatible results with all 5 packed red blood cells. Additional blood type antigen and antibody tests confirmed the anti-Ge alloantibody. While rare, cases of hemolytic transfusion reaction or hemolytic disease in newborns due to anti-Ge have been recently reported in the literature. Therefore, additional further studies on alloantibodies to high-incidence antigens, including anti-Ge, are necessary in the future. The Korean Society for Laboratory Medicine 2012-11 2012-10-17 /pmc/articles/PMC3486941/ /pubmed/23130346 http://dx.doi.org/10.3343/alm.2012.32.6.442 Text en © The Korean Society for Laboratory Medicine. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Jeon, You La
Park, Tae Sung
Cho, Sun Young
Oh, Seung Hwan
Kim, Myeong Hee
Kang, So Young
Lee, Woo-In
The First Korean Case Report of Anti-Gerbich
title The First Korean Case Report of Anti-Gerbich
title_full The First Korean Case Report of Anti-Gerbich
title_fullStr The First Korean Case Report of Anti-Gerbich
title_full_unstemmed The First Korean Case Report of Anti-Gerbich
title_short The First Korean Case Report of Anti-Gerbich
title_sort first korean case report of anti-gerbich
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486941/
https://www.ncbi.nlm.nih.gov/pubmed/23130346
http://dx.doi.org/10.3343/alm.2012.32.6.442
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