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Frequencies of 23 Functionally Significant Variant Alleles Related with Metabolism of Antineoplastic Drugs in the Chilean Population: Comparison with Caucasian and Asian Populations

Cancer is a leading cause of death worldwide. The cancer incidence rate in Chile is 133.7/100,000 inhabitants and it is the second cause of death, after cardiovascular diseases. Most of the antineoplastic drugs are metabolized to be detoxified, and some of them to be activated. Genetic polymorphisms...

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Detalles Bibliográficos
Autores principales:	Roco, Ángela, Quiñones, Luis, Agúndez, José A. G., García-Martín, Elena, Squicciarini, Valentina, Miranda, Carla, Garay, Joselyn, Farfán, Nancy, Saavedra, Iván, Cáceres, Dante, Ibarra, Carol, Varela, Nelson
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2012
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487109/ https://www.ncbi.nlm.nih.gov/pubmed/23130019 http://dx.doi.org/10.3389/fgene.2012.00229

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