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Interleukin-1 Mediates Neuroinflammatory Changes Associated With Diet-Induced Atherosclerosis
BACKGROUND: Systemic inflammation contributes to brain pathology in cerebrovascular disease through mechanisms that are poorly understood. METHODS AND RESULTS: Here we show that atherosclerosis, a major systemic inflammatory disease, is associated with severe cerebrovascular inflammation in mice and...
Autores principales: | Denes, Adam, Drake, Caroline, Stordy, Jing, Chamberlain, Janet, McColl, Barry W., Gram, Hermann, Crossman, David, Francis, Sheila, Allan, Stuart M., Rothwell, Nancy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487321/ https://www.ncbi.nlm.nih.gov/pubmed/23130147 http://dx.doi.org/10.1161/JAHA.112.002006 |
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