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Histone Deacetylase Activity Selectively Regulates Notch-Mediated Smooth Muscle Differentiation in Human Vascular Cells

BACKGROUND: Histone deacetylases (HDACs) modify smooth muscle cell (SMC) proliferation and affect neointimal lesion formation by regulating cell cycle progression. HDACs might also regulate SMC differentiation, although this is not as well characterized. METHODS AND RESULTS: Notch signaling activate...

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Detalles Bibliográficos
Autores principales:	Tang, Yuefeng, Boucher, Joshua M., Liaw, Lucy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487326/ https://www.ncbi.nlm.nih.gov/pubmed/23130137 http://dx.doi.org/10.1161/JAHA.112.000901

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